2024 Consomic strain

Consomic strain

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August undefined, 2024

WebMar 1, 2003 · Like the consomic strains, these congenic strains also represent a renewable resource. The use of congenic strains has been very limited until this time because development of a congenic line typically requires 10–12 generations of backcrossing, after completion of the crossbreeding studies to define the QTL of interest. ... WebNov 24, 2024 · Here, we utilized the A/J-11SM consomic strain and a set of chromosome 11 (Chr. 11) congenic strains developed from A/J-11SM to identify a candidate STZ-induced diabetes susceptibility gene.

Chromosome Substitution Strain - an overview - ScienceDirect

Webany consomic strain within 6 months, by an F2 intercross of the consomic with the background parental strain. These rats are likely to become a national resource for rat research. The website, which currently gets 2,000 visits per month (figure 3), enables investigators to download data or to use the analytical WebTwo consomic mouse strains (C3H-Chr 11 NSY and C3H-Chr 14 NSY ) were previously established using the speed congenic method [5]. Congenic lines were produced as previously described [28] by... body glove iphone se case

Consomic mouse strain selection based on effect size …

WebStrain State: Strain Type: Any closed colony coisogenic strain congenic strain consomic or chromosome substitution strain hybrid inbred strain major histocompatibility congenic minor histocompatibility congenic mutant stock mutant strain noninbred stock outbred stock recombinant congenic recombinant inbred segregating inbred unclassified wild ... WebFeb 18, 2013 · Background. We have established 17 Y chromosome consomic (hereafter Y-consomic) mouse strains in an inbred DH/Sgn (hereafter DH) strain. There was a wide spectrum of variation in body weight and testis weight among the Y-consomic mouse strains [1, 2].Thus, it was expected that there were Y-linked genes associated with body … WebMar 3, 2010 · Chromosome 13 consomic and congenic rat strains were analyzed to investigate the pattern of genomic pathway utilization involved in protection against salt-sensitive hypertension and renal injury. Introgression of the entire Brown-Norway chromosome 13 (consomic SS-13(BN)) or nonoverlapping segments … body glove isup pump

consomic strain

WebNov 24, 2024 · These strains allow reproducible and efficient whole-chromosome mapping (Flint and Eskin, 2012 ). In contrast, consomic strains, also termed chromosome substitution strains, possess a substitution of one whole chromosome pair from the donor strain into the genetic background of the host strain. WebJul 23, 2024 · The congenic strain R3 (C3H.NSY- [ D11Mit242-D11Mit168 ]) possessed the middle and distal region (segment C, D and E) of NSY-Chr 11 from the recombinant position between D11Mit274 and D11Mit242 to the telomere of Chr 11. gleaner twitterWebFeb 27, 2024 · To assess the role of ChrY genetic variation on susceptibility to IAV infection, we studied male mice from a panel of 11 B6-ChrY consomic strains of mice using mouse-adapted Puerto Rico A/PR/8/34 H1N1 (PR8) IAV by challenging them with 5 × 10 3 egg infectious units (EIU), equivalent to ∼1 B6-LD 50.A significant overall effect of strain on … body glove iphone xr case

"WebConsomic strains, also known as chromosome substitution strains, are powerful tools for assigning polygenes that control quantitative complex traits to specific … " - Consomic strain

Consomic strain

Identification of Genetic Determinants of the Sexual Dimorphism

WebA consomic rat strain is one in which an entire chromosome is introgressed into the isogenic background of another inbred strain using marker-assisted selection. The … WebB. Consomic Strains The process of generating congenic strains is very lengthy, because it takes many backcrosses to obtain an isogenic or homogeneous background. …

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WebConsomic strains are a variation on congenic strains in which a whole chromosome — rather than one local chromosomal region — is backcrossed from a donor strain onto a recipient background. In almost all cases, the donor chromosome is the Y. Like … Inbreeding depression will not occur when a new inbred strain is begun with two … 9.2 RECOMBINANT INBRED STRAINS 9.2.1 Overview 9.2.1.1 … J:301 Snell GD, Preliminary data on crossing-over between H-2, and Fu, Ki …

WebNov 1, 2015 · This creates the consomic strain that shares with its host strain the same 1) genetic background (including chrY PAR, autosomes, chrX, mitochondrial DNA) and 2) pre- and postnatal maternal environment (including inoculated microbiota). WebNov 24, 2008 · Consomic strains have recently attracted attention as an advantageous method to screen for genes related to developmental, physiological, and behavioral phenotypes. Recently, a new set of consomic strains was established from the Japanese wild-derived mouse strain MSM/Ms and C57BL/6JJcl. By analyzing the entire consomic …

WebApr 1, 2008 · Genomes of consomic mouse strains. Centromeres are shown at the top. (Green) MSM/Ms-derived chromosomes; (blue) B6 chromosomes. The genetic background and mitochondria DNA were confirmed to be ... WebDec 2, 2024 · Consomic rat strains, in which an entire chromosome has been introgressed into the isogenic background of another strain, offer a rapid approach to mapping a trait to a chromosome [57]. ... An adult consomic rat’s mediastinal dissection and aortic injection exhibit the passage of contrast from the aorta to the major pulmonary artery through a ...

WebB. Consomic Strains The process of generating congenic strains is very lengthy, because it takes many backcrosses to obtain an isogenic or homogeneous background. Consomic strains are rat strains in which a whole chromosome from one strain is transferred to the genomic background of another strain.

WebA consomic strain of animals is an inbred strain in which a whole chromosome – rather than one local chromosomal region – is replaced from a donor strain onto a recipient background. This is performed by marker-assisted breeding; the donor strain is backcrossed to the recipient strain for over eight generations and progeny (generally … gleaner twitter jamaicaWebOct 1, 2010 · The consomic strains for Chrs 5, 7C, 10, and X could not be characterized in this study because of some difficulties with breeding and analyses. Each consomic strain was described as B6-ChrN MSM, in which N was the number of the chromosome transferred from the MSM strain. body glove isup reviewWebNov 24, 2024 · In contrast, consomic strains, also termed chromosome substitution strains, possess a substitution of one whole chromosome pair from the donor strain into … gleaner tripshttp://informatics.jax.org/silver/chapters/3-3.shtml gleaner twin rotorWebMar 3, 2010 · Chromosome 13 consomic and congenic rat strains were analyzed to investigate the pattern of genomic pathway utilization involved in protection against salt … body glove kids sandals pitchWebB. Consomic Strains The process of generating congenic strains is very lengthy, because it takes many backcrosses to obtain an isogenic or homogeneous background. … body glove kids breathe free maskWebConsomic strains Consomic inbred strains are also created through successive backcrossing to a different inbred strain, but the choice of breeders is based on an entire … body glove kids clothes