WebJan 28, 2024 · FGD5-AS1 attenuate the growth and calcification but induced apoptosis of high glucose-treated HA-VSMC cells. These results suggest that FGD5-AS1 are …
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WebLncRNA FGD5-AS1, also known as miR-5590-3p, is involved in the regulatory role of ceRNA in many cancers. However, the roles of lncRNA FGD5-AS1 or miR-5590-3p in … WebFeb 23, 2024 · In this study, FGD5-AS1 was proved to be a ZEB1-related lncRNA which was overexpressed and predicted poor prognosis in GC. Knockdown of FGD5-AS1 decreased GC proliferation and metastasis in vitro and in vivo. EMT is proved to be an important factor in the poor prognosis of gastric cancer. The oncogene ZEB1 is known to …
WebLncRNA FGD5-AS1 has been reported as a potential oncogene in ovarian cancer (OC). The present paper focused on the action mechanism of FGD5-AS1 in OC. Clinical OC samples were collected for expression analyses of FGD5-AS1, RBBP6, and miR-107. The expression of FGD5-AS1, RBBP6, and miR-107 in OC cells was altered by transfection. WebApr 29, 2024 · Overexpression of FGD5-AS1 enhanced proliferation, migration, angiogenesis, and permeability of HUVEC. This effect is achieved through activation of …
WebOct 15, 2024 · FGD5-AS1 expression is known to regulate cell proliferation, migration, invasiveness, drug resistance, and EMT by modifying different pathways, including the hsa-miR-107/FGFRL1 pathway, the Wnt/β-catenin pathway, the miR-302e/CDCA7 pathway, and miR-520b/USP21 pathway in different cancers. However, the specific regulatory … WebJan 20, 2024 · This study is aimed at assessing the potential prognostic significance of autophagy-related long noncoding RNA (ARlncRNA) in colorectal cancer (CRC). 3145 ARlncRNAs were obtained from autophagy-related genes (ARGs) by Pearson correlation analysis, and we established a competing endogenous RNA (ceRNA) network mediated …
WebOct 15, 2024 · Accumulating evidence has elucidated the biological function of lncRNAs in various tumors. FGD5 antisense RNA 1 (FGD5-AS1) is identified as a significant tumor regulator in malignancies. Up to now, the detailed function of FGD5-AS1 in cervical cancer and its underlying molecular mechanisms remain uninvestigated. Bone marrow stromal …
WebJun 29, 2024 · 摘要: 目的探讨FGD5-AS1对高糖诱导的肾小管上皮细胞HK-2肿瘤坏死因子-α(TNF-α)和白细胞介素-6(IL-6)表达、细胞凋亡的影响及其机制。 方法25 mmol/L葡萄糖诱导HK-2细胞24 h后,RT-qPCR检测细胞中FGD5-AS1和miR-519d-3p表达量。分别转染FGD5-AS1过表达载体(pcDNA-FGD5-AS1)、miR-519d-3p抑制剂或共转染pcDNA-FGD5-AS1 … triathlon in houstonWebOct 18, 2024 · FGD5-AS1 regulates oral squamous cell carcinoma via competitively binding to miR-520b against USP21. The inhibiting effects of FGD5-AS1 knockdown on colorectal cancer (CRC) cell proliferation, migration, and invasion, and the promoting effects on CRC cell apoptosis could be revived by miR-302e suppression or CDCA7 upregulation. triathlon in jacksonville ncWebMay 11, 2024 · FGD5-AS1 was selected for further study since all its targets were CHD-related genes (NRAS, PTEN, and SMAD4). Both FGD5-AS1 and SMAD4 could bind with hsa-miR-421, which has been validated using dual-luciferase reporter assays. Knockdown of FGD5-AS1 not only significantly reduced PTEN and SMAD4 expression in HEK 293 and … triathlon in japanWebDec 14, 2024 · Moreover, it was identified that FGD5‑AS1 acted as a molecular sponge for microRNA (miR)‑142, and FGD5‑AS1 enhanced the resistance of A549/DDP cells to DDP by directly interacting with miR‑142. Programmed cell death 1 ligand 1 (PD‑L1) was also found to be a key effector of the FGD5‑AS1/miR‑142 axis to regulate the … ten toys by geraldine clyneWebSep 9, 2024 · Long non-coding RNA transmembrane and coiled-coil domain family 1 antisense RNA 1 (TMCC1-AS1) has been frequently reported to be associated with prognosis in patients with liver cancer (LC). However, the biological role of TMCC1-AS1 in LC in vitroremains unclear. ten town youtubeWeb葡萄糖(批号G8270)、甘露醇(批号PHR1007)购自美国Sigma公司;乱序无意义阴性序列(si-NC)、miR-302a-3p寡核苷酸模拟物(miR-302a-3p mimics)及mimic 阴性对照序列(miR-NC)、FGD5-AS1小分子干扰RNA(si-FGD5-AS1)购自广州锐博生物科技有限公司;Trizol试剂(批号20241003)购自上海联迈生物工程 ... ten town tv seriesWebWe identify 15 prognostic pyroptosis-related lncRNAs (ZNF667-AS1, OIP5-AS1, AL118506.1, AF117829.1, POC1B-AS1, CCDC18-AS1, THUMPD3-AS1, FLNB-AS1, SNHG11, HCG18, AL021707.2, UGDH-AS1, LINC00641, FGD5-AS1 and AC245452.1) from the TCGA-COAD dataset and use them to construct the risk model. After then, this … triathlon in hawaii