Host induced gene silencing
WebAug 24, 2015 · Another alternative is the use of host-induced gene silencing (HIGS) methods, which exploit the silencing effect of small interfering RNA (siRNA) signals in interacting organisms, and involves host expression of siRNA-generating constructs directed against genes in associated pathogens, parasites or symbionts (Knip et al ., 2014 ). Web8 rows · Mar 28, 2024 · Host-induced gene silencing (HIGS) technology has emerged as a powerful alternative to chemical ...
Host induced gene silencing
Did you know?
WebOct 8, 2024 · The Sscnd1 gene-silenced strains exhibited a defect in compound appressorium formation and cell integrity. The instantaneous silencing of Sscnd1 by tobacco rattle virus (TRV)-mediated host-induced gene silencing (HIGS) resulted in a significant reduction in disease development in tobacco. WebNatural Host-Induced Gene Silencing Offers New Opportunities to Engineer Disease Resistance Yingnan Hou 1 ,2 *and Wenbo Ma RNA silencing is an essential gene-regulation mechanism in eukaryotic organisms. Guided by small RNAs (sRNAs) of 20–25 nt in length, RNA silencing broadly governs a wide range of bio-logical processes.
WebMay 23, 2024 · Generation of dsRNAs with homology to genes of a pathogen may lead to reduced transcript abundances of the target genes, a process referred to as host-induced gene silencing (HIGS). Several reports describe the use of HIGS in plants for developing strong resistance against Fusarium spp. (Table 1 ). WebMar 15, 2024 · Virus-induced gene silencing (VIGS) is an RNA-mediated reverse genetics technology that has evolved into an indispensable approach for analyzing the function of genes. It downregulates endogenous genes by utilizing the posttranscriptional gene silencing (PTGS) machinery of plants to prevent systemic viral infections. Based on …
WebWe demonstrate that host-induced gene silencing (HIGS) targeting the fungal sterol 14α-demethylase ( CYP51) genes restricts Fusarium infection in plants. Fusarium diseases have a significant impact not only on global … WebApr 28, 2024 · This cross-kingdom RNAi based gene silencing phenomenon is called host induced gene silencing (HIGS), which has been demonstrated to successfully suppress disease development caused by fungi (including biotrophs, hemibiotrophs, and necrotrophs) as well as oomycetes ( Govindarajulu et al., 2015; Park et al., 2016; Song and Thomma, …
WebJul 22, 2024 · Based on the discovery of RNAi in animal cells, an innovative RNAi-based approach was developed and has been applied in controlling filamentous pathogens. Host-induced gene silencing (HIGS) is used to produce artificial siRNAs in plants to silence pathogen genes that are required for infection (Figure 1c). Several studies have …
WebMar 28, 2024 · Taken together, the results of this study suggest that the ToCV CPm protein possesses the dual activities of pathogenicity and RNA silencing, which might inhibit host post-transcriptional gene silencing (PTGS)-mediated resistance and is pivotal in the primary process of ToCV infecting hosts. chat service client sfrWebJun 16, 2024 · RNA silencing in plants was first identified as a post-transcriptional mechanism in transgenesis and viral infection 1, 2. It is triggered by viral or transgene RNA, and key intermediate... customized keychain onlineWebMar 10, 2024 · We show that host-induced gene silencing is an effective method for eliminating this toxin in transgenic maize. We transformed maize plants with a kernel … customized key caps texturedWebAug 25, 2024 · Host-induced gene silencing (HIGS) refers to the silencing of genes in pathogens and pests by expressing homologous double-stranded RNAs (dsRNA) or … customized keychains cheapWebApr 19, 2024 · In this regard, Host Induced Gene Silencing (HIGS) has shown promising results where host-derived immunity is attained by rendering small interfering RNAs (sRNA) into the pathogen for silencing of the targeting genes that … customized keycaps corsair keyboardWebJun 1, 2024 · In the present study, host-induced gene silencing (HIGS), developed based on RNA interference (RNAi), was applied to protect B. napus from S. sclerotiorum infection. Three pathogenicity genes, the endo-polygalacturonase gene (SsPG1), cellobiohydrolase gene (SsCBH), and oxaloacetate acetylhydrolase gene (SsOAH1), were chosen as HIGS … chat service providersWebMay 23, 2024 · MicroRNAs (miRNAs) are essential regulators of gene expression in humans and can control pathogenesis and host–virus interactions. Notably, the role of specific host miRNAs during influenza virus infections are still ill-defined. The central goal of this study was to identify novel miRNAs and their target genes in response to influenza virus … customized keychain flashlight