NettetPurpose: This study investigated the migration effect of EPCs labeled with a multimodal imaging agent in a murine ischemic hindlimb model, using magnetic resonance imaging (MRI) ... Mouse model of hindlimb ischemia and EPC transplantation. To generate hindlimb ischemia, male athymic nude mice (15–20 g weight, 5 weeks of age) ... Nettet5. nov. 2024 · To evaluate the pro-angiogenic activity of pExo in vivo, a hind limb ischemia (HLI) model in db/db diabetic mice was used. After surgical induction of HLI on Day 0, ...
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Nettet23. jun. 2003 · Mouse Model of Unilateral Hindlimb Ischemia Under narcosis with intramuscular xylazine (40 mg/kg) and ketamine (100 mg/kg), 12-week-old C57BL/6 and CD4 −/− mice (Jackson Laboratories, Bar Harbor, Maine) underwent surgical ligation of the left femoral artery to create unilateral hindlimb ischemia (n=14 per group). 6 The … Nettet1. mar. 2005 · Radiolabeled RGD peptides that target αvβ3 integrin are promising tracers for imaging tumor angiogenesis. Integrins and angiogenesis also play important roles in healing of ischemic lesions. Thus, we investigated the biodistribution of radiolabeled RGD and expression of αv integrin in a mouse model of hindlimb ischemia. Methods: 125I … shepherd montana real estate
Mouse hindlimb ischemia
NettetThe purpose of the present study was to evaluate two fluorophore-conjugated peptide probes specific to VEGFR and MMP for dual-targeted in vivo monitoring of … Nettet20. apr. 2016 · Vascular endothelial growth factor receptor (VEGFR) and matrix metalloproteinase (MMP) are up-regulated in ischemic tissue and play pivotal roles in promoting angiogenesis. The purpose of the present study was to evaluate two fluorophore-conjugated peptide probes specific to VEGFR and MMP for dual-targeted … Nettet26. jul. 2024 · Similarly, Iwase et al. used an animal model of hindlimb ischemia with male Lewis rats who received rat bone marrow-derived MSCs (rBM-MSCs) (5 × 10 6 cells) or rat bone marrow-derived mononuclear cells (rBM-MNC) (5 × 10 6 cells) to demonstrate the presence and viability of rBM-MSCs in the interstitial tissues three weeks after … sprigler door service new albany indiana