WebbThe histogenesis of sarcomatoid urothelial carcinoma, a rare neoplasm with bidirectional epithelial and mesenchymal differentiation, has been a matter of controversy. To clarify its origin, we analysed the status of X-chromosome inactivation in sarcomatoid urothelial … Webb12 jan. 2014 · The sarcomatoid variant is characterized by an atypical spindle tumor; it shows focal positivity for uroplakin II and negativity for uroplakin III. Small cell carcinoma is characterized by poorly differentiated tumor cells with large nuclei and scant cytoplasm and shows negative staining for uroplakin II and uroplakin III. Table 3
TERT promoter mutation status in sarcomatoid urothelial …
WebbSarcomatoid urothelial carcinoma is an aggressive disease, of rapid and torpid onset which occurs in patients of advanced age and smokers. There are no established treatment guidelines, and it appears that no treatment influences increased survival. Cystectomy … Webb31 mars 2016 · Urothelial carcinoma (UCa) is the most common type of bladder cancer in the United States, accounting for greater than 90% of reported bladder cancer cases each year. 1 Numerous histologic variants of UCa have been described and several of these … chesterton oil cutter product
Cancers Free Full-Text Unusual Faces of Bladder Cancer
WebbBackground and objectives: Angiosarcomas are uncommon and extremely aggressive malignancies derived from vascular endothelial cells. Although they can occur anywhere in the body and at any age, they are more frequently found in the skin of the head and neck regions and in the elderly. Few cases have been recorded in deep soft tissues and in … Webb1 apr. 2024 · Sarcomatoid urothelial carcinoma (SUC) is a rare urothelial variant, recognized as a distinct pathologic entity by WHO 2016 classification of urinary tract tumors. 1 It can be encountered in approximately 0.1% to 0.3% of all bladder malignancies, predominantly affecting older adults and demonstrating a male predilection, while it has … Webb27 okt. 2024 · Clinical practice allows the pathologist to face unusual histological subtypes of urothelial carcinomas (UC), and conventional TCC displaying focal/extensive morphologic variations of uncertain significance. This narrative collects 25 years of personal experience of the authors in the routine diagnosis of bladder cancer. 2. chesterton on gratitude