Slc gene family
The solute carrier (SLC) group of membrane transport proteins include over 400 members organized into 66 families. Most members of the SLC group are located in the cell membrane. The SLC gene nomenclature system was originally proposed by the HUGO Gene Nomenclature Committee (HGNC) and is the … See more By convention of the nomenclature system, members within an individual SLC family have greater than 20-25% sequence identity to each other. In contrast, the homology between SLC families is very low to non-existent. … See more The following families are named under SLC: 1. high-affinity glutamate and neutral amino acid transporter See more Putative SLCs, also called atypical SLCs, are novel, plausible secondary active or facilitative transporter proteins that share ancestral background with the known SLCs. The atypical … See more Most members of the SLC group are located in the cell membrane, but some members are located in mitochondria (the most notable one being SLC family 25) or other intracellular organelles. See more Names of individual SLC members have the following format: where: • SLC is the root name (SoLute Carrier) • n = an integer representing a family (e.g., 1-52) • X = a single letter (A, B, C, ...) denoting a subfamily See more • Outline of families • Datasets and Reagents on the Solute Carrier Family • List of proteins at HGNC website See more WebSolute carrier (SLC) family transporters utilize an electrochemical potential difference or an ion gradient generated by primary active transporters for transporting their substrates …
Slc gene family
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WebThe SLC8 gene family of sodium-calcium exchangers (NCX) - Structure, function, and regulation in health and disease. Mol Aspects Med. 2013 Apr;34(2-3):220-35. SLC name WebJun 21, 2024 · Abnormalities in SLC function in the kidney or placenta may be related to the volume abnormalities observed with this disease. For these reasons, this study aimed to investigate whether 263 haplotype tagging single-nucleotide polymorphisms (SNPs) in 26 members of the SLC gene family are associated with preeclampsia in white and black …
WebThe solute-carrier gene (SLC) superfamily encodes membrane-bound transporters. The SLC superfamily comprises 55 gene families having at least 362 putatively functional protein … Websolute carrier family 2, facilitated glucose transporter member 7: SLC2: SLC2A8: SLC2A8: solute carrier family 2, facilitated glucose transporter member 8: SLC2: SLC2A9: SLC2A9: …
WebApr 1, 2009 · Many of these transporters belong to the solute-carrier (SLC) gene superfamily, and include passive transporters, sym-porters and antiporters, as well as mitochondrial and vesicular transporters. The SLC superfamily comprises 55 gene families, having at least 362 putatively functional protein-coding genes . WebNational Center for Biotechnology Information
WebApr 19, 2024 · Given the important role of SLC family in essential physiological processes including nutrient uptake, ion transport, and waste removal, and that their dysregulation …
WebFeb 1, 2009 · The solute carrier (Slc) superfamily is a major group of membrane transport proteins present in mammalian cells. Although Slc transporters play essential and diverse roles in the central... jaw is throbbingWebDec 2, 2024 · Emerging pieces of evidence indicate that the mutation or functional change in the SLC39A family genes leads to the development and progression of multiple malignancies, such as colorectal cancer, breast cancer, esophageal cancer, hepatocellular carcinoma, pancreas cancer, gastric cancer, prostate cancer, and lung cancer ( Hoang et … jawitz head office contact detailsWebApr 10, 2024 · Jeffrey D. Allred, Deseret News. Many had seen Sapporo and Salt Lake City as the strongest 2030 bids, suggesting that Sapporo would be chosen to host in 2030 and Salt Lake City in 2034. However, that was before an Olympic scandal surfaced involving the 2024 Summer Games in Tokyo. The impact on public opinion of that scandal, tied to … low rbc nursing diagnosisWebThe overview of human SLC superfamily. The human SLC superfamily comprises 386 member proteins that transport a broad spectrum of substrates, such as nutrients, toxins, and prescription drugs. The superfamily members are classified into 52 families, based on the number of predicted or observed transmembrane a-helices (usually 10–14) and ... jaw is tight and soreWebThe SLC superfamily currently includes 458 transport proteins in 65 families that carry a wide variety of substances across cellular membranes. While members of this superfamily are found throughout cellular organelles, this review focuses on transporters expressed at the plasma membrane. low rbc normal hgbjawitz agencies privateWebOct 21, 2024 · The largest groups are SLC family 6 (15 genes), SLC family 2 (14 genes), and SLC family 16 (13 genes) ( Table S5 ). Larger SLC families appear to have several independent origins. SLC family 25, for instance, is composed of 3 large groups of orthologous genes, plus few groups of more recent origin. low rbc men