Tle3 in cancer
WebAug 18, 2015 · This association between TLE3 staining and outcome among women treated with taxanes was subsequently validated in independent cohorts of triple negative breast cancer patients (Kulkarni et al ... WebExpression of TLE3 in cancer - Summary - The Human Protein Atlas TLE3 PATHOLOGY CANCER ANTIBODIES AND VALIDATION Dictionary Human pathology PROGNOSTIC SUMMARYi Prognostic marker in cervical cancer (favorable) Cervical cancer p<0.001 RNA EXPRESSION OVERVIEWi TCGA dataseti RNA cancer category: Low cancer specificity
Tle3 in cancer
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WebApr 4, 2024 · Here we report that the transcriptional corepressor TLE3 is a guardian of luminal cell fate in breast cancer and operates independently of the estrogen receptor. In luminal breast cancer, TLE3 actively repressed the gene-expression signature associated with highly aggressive basal-like breast cancers (BLBC). WebAug 31, 2024 · TLE3, β-tubulin class III, and GSTP1 were expressed in 24 cases (46.2%), 21 cases (40.4%) and 24 cases (46.2%), respectively, among the 52 patients investigated. …
WebTLE3, β-tubulin class III, and GSTP1 were expressed in 24 cases (46.2%), 21 cases (40.4%) and 24 cases (46.2%), respectively, among the 52 patients investigated. The expression of … WebApr 4, 2024 · Here we report that the transcriptional corepressor TLE3 is a guardian of luminal cell fate in breast cancer and operates independently of the estrogen receptor. In …
WebProteini. Full gene name according to HGNC. TLE family member 3, transcriptional corepressor. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. TLE3 (ESG, ESG3, GRG3, HsT18976, KIAA1547) Protein classi. Assigned HPA protein class (es) for the encoded protein (s). WebExpression of TLE3 (ESG, ESG3, GRG3, HsT18976, KIAA1547) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers.
WebFeb 7, 2024 · To determine the TLE3-regulated transcriptome in luminal breast cancer cells, transient silencing of TLE3 was carried out using siRNAs targeting TLE3 (siTLE3), FOXA1 (siFOXA1), or a non-silencing control (siNS) in T47D, MDA-MB-453, and SKBR3 breast cancer cell lines. At 48 hours post-transfection, RNA was collected and prepared for sequencing.
mehron white powderWebIn conclusion, the present study demonstrated that miR-3677 promoted BC cell proliferation, migration and invasion by inhibiting TLE3 expression, which provided a novel mechanism and a promising therapeutic target for patients with BC. Keywords: breast cancer; cell metastasis; cell proliferation; microRNA-3677; transducin-like enhancer of Split3. nans leadershipWebThis section shows a general overview of the selected mutation. It describes the source of the mutation i.e gene name/sample name/tissue name with unique ID, and also shows the mutation syntax at the amino acid and nucleotide sequence level. mehr organizationWebNov 1, 2024 · Recent studies have revealed that TLEs are dysregulated in certain human cancer types and may function as oncogenes or tumor suppressors in different contexts. ... TLE3 ubiquitination and ... mehrotra biotech private limitedWebJan 25, 2024 · In luminal breast cancer, TLE3 actively repressed the gene expression signature associated with highly aggressive basal-like breast cancers (BLBC). Moreover, maintenance of the luminal lineage ... mehroom the lyricsWebDec 19, 2024 · Together, our findings reveal a mechanistic link between TLE3 and GR-mediated resistance to AR inhibitors in human prostate cancer. Keywords: Enzalutamide; … mehro the same lyricsWebNew selective, efficacious chemotherapy agents are in demand as traditional drugs display side effects and face growing resistance upon continued administration. To this end, bioactive molecules such as peptides are attracting interest. RT2 is a cationic peptide that was used as an antimicrobial but is being repurposed for targeting cancer. In this work, … mehroom colour in english